The coronaviruses are capable of adapting to new environments through mutation and recombination hence, they can alter host range and tissue tropism efficiently ( 5). However, coronaviruses had their first appearance in 1960 and two other highly pathogenic events of this type of viruses have already happened, SARS-CoV that emerged in Southern China in 2003 ( 3) and Middle East Respiratory Syndrome-Related CoV (MERS-CoV), which appeared in Saudi Arabia in 2012 ( 4). The first case of that virus was identified in Wuhan, the capital city of Hubei Province, China, in December 2019 ( 2), and in January 2020, the COVID-19 has become a worldwide pandemic. The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and its disease, COVID-19, have been considered a pandemic spread and the most devastating global event in modern medicine ( 1). Thus, this review can further researchers in the developing of masks to decrease the spread of a pandemic disease. Moreover, the review also brought possibilities of masking the population, which already have been done in countries such as China and Korea and ways of sterilization for reuse of PPE during COVID-19 outbreak. It also makes an analysis of masks composed of nanotechnology which provide high filtration efficiency. The results of the review showed that most of the masks used cotton, nylon, silver fiber fabrics, among others as fabrics to develop the masks. Here, an overview of the main materials used in the mask manufacturing and their efficiency was described. After the process of screening and eligibility, 563 patents were selected for our analysis according to the aim of the study which used masks such as a PPE against dust particles and pathogens, mostly when it is about airborne transmission, such as viruses and bacteria. The review was carried out in the patent database in the period of May 2019 to May 2020. Thus, we performed a patent review to evaluate the current patents related to the protective mask. Due to the high transmission of this disease, rate precautions have been implemented, such as the use of masks by the population, personal protective equipment (PPE), and safety protocols, mainly to health workers. Since January 2020, the World Health Organization announces COVID-19 outbreak a case of public health emergency of international interest, and declaring it a pandemic on March.
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